Peptide-Enhanced Cross-Linked HA
First-of-its-kind CE-approved formulation integrating cross-linked hyaluronic acid with biomimetic peptides CG-BOOSTRIN and CG-GLAMERIN. Immediate correction. Progressive biological renewal.
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Cross-linked HA matrix provides immediate volumetric filling and wrinkle correction at the point of injection.
Optimised G' of 200 Pa enables precise facial contouring while allowing natural expression retention.
Peptide modulation prevents excessive osmotic water attraction, avoiding the oedematous appearance seen with standard HA fillers.
CG-GLAMERIN signals fibroblasts to upregulate Type I collagen synthesis, the primary structural protein of the dermis.
Endogenous hyaluronic acid production increases, supporting long-term dermal hydration independent of the injected HA.
Progressive extracellular matrix renewal continues for months post-treatment, yielding sustained skin quality improvement.
The ELYARA Plus formulation integrates two precisely selected biomimetic peptides directly into the cross-linked HA matrix: not as surface additions, but as structural components of the hybrid molecule itself.
Inhibits hyaluronidase, the enzyme responsible for HA breakdown, slowing degradation and extending treatment longevity beyond conventional fillers.
Stimulates collagen and elastin synthesis in dermal fibroblasts, driving progressive structural renewal in the ECM long after the initial treatment session.
Active Peptide Complex
Superficial fine lines, nasolabial folds, perioral rhytids, and mid-face lines requiring subtle, precise volumisation with natural texture.
Micro-injection techniques to improve overall skin texture, radiance, and elasticity across the face and décolletage.
Subtle volume definition and natural lip movement retention. Lower G' allows flexible, authentic results without rigidity.
Tear trough correction in patients where a softer, mid-density formulation is required for smooth integration with delicate periorbital tissue.
Cheek mid-zone softening and light volumisation where structural contouring is secondary to textural improvement and skin quality.
Ideal maintenance phase treatment following Ultra. Lower density sustains Bio-stimulation benefits between structural top-up sessions.
| Feature | ELYARA Plus | ELYARA Ultra |
|---|---|---|
| Primary Indication | Fine lines, mid-dermal refinement | Structural contouring, volume restoration |
| Elasticity G' | 200 Pa | 400 Pa |
| Injection Depth | Mid to Deep Dermis | Mid to Deep Dermis |
| Longevity | 9 to 12 Months | 12 to 18 Months |
| Needle Gauge | 27G | 27G |
| Volume | 1 × 1 mL Syringe | 1 × 1 mL Syringe |
| CE Approved | Yes | Yes |
| Peptide Complex | CG-BOOSTRIN + CG-GLAMERIN | CG-BOOSTRIN + CG-GLAMERIN |
Request a product sample kit, full clinical data including the 81% collagen I increase study, and injection technique documentation. Available to accredited clinics and verified distributors.